Regenerative Medicineregenerative medicine

We invested at the founding of Tele Bio Inc., a certified venture originating from Jichi Medical University, and through joint research we provide research reagents related to regenerative medicine, including human adipose-derived stem cell secretome.

Key Features of the Stem Cell Secretome (Proprietary Technology)

  • First in the world to develop stem cell secretome that is purified, concentrated, and standardized using proprietary technology.
  • Removes impurities (such as ammonia and lactic acid) and increases the concentration of hepatocyte growth factor (HGF), which is considered important for tissue regeneration.

Three Potential Benefits of the Stem Cell Secretome

  • 1) Tissue repair and protection
  • 2) Anti-inflammatory effects
  • 3) Anti-fibrotic effects

Various effects are expected from secreted factors (stem cell secretome) released by human mesenchymal stem cells.
Autologous stem cell therapy has shown benefits for a wide range of diseases, but manufacturing and quality management are complex, costs are very high, and access is limited to a small number of affluent patients.
With Tele Bio’s advanced proprietary technology—developed by Professor Kotaro Yoshimura, a world authority in this field—manufacturing high-quality, stable stem cell secretome has been made easier and more affordable. The stem cell secretome may offer effects comparable to autologous stem cell therapy.

*Research reagent: Purified extract (lyophilized) from cultured supernatant of human adipose-derived stem cells—high in bioactive substances, low in toxicity, and with stable quality.

Research Reagent: Human Adipose-Derived Stem Cell “Stem Cell Secretome”

Stem Cell Secretome

This is a lyophilized culture supernatant of human adipose-derived stem cells, rich in bioactive substances such as HGF (Hepatocyte Growth Factor) and characterized by low toxicity. It can reproduce biological functions mediated by stem-cell-secreted factors in vitro and in vivo. We offer two products—120 TBU and 500 TBU—with different HGF contents.

*TBU stands for Tele Bio Unit. 500 TBU contains 500,000 pg/vial of HGF, and 120 TBU contains 120,000 pg/vial.

• Contains highly concentrated bioactive substances (including HGF).
• Low toxicity (low ammonia concentration) and low endotoxin levels.
• Quality is stable with minimal vial-to-vial variation due to standardized concentration and formulation.
• Sterilized.
• Tested for major viruses (two-step testing of donor blood at collection and the final product).